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横带和中枢神经的年龄相关变化:一个尸体组织学和生物力学研究

Apichaya Niyomchan¹, Akkradate Siriphorn², Kanet Kathinted¹

¹Department of Anatomy, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

|March 2, 2026

概括

横手带 (TCL) 随着年龄的增长而变硬和混乱,以及中枢神经退化. 这些与年龄相关的变化可能会增加老年人手掌道综合征的风险.

科学领域:

整形外科整形外科整形外科
老年学是一门学科.
人体解剖学解剖学解剖学

背景情况:

横带 (TCL) 和中枢神经的与年龄相关的变化与老年人肌道综合征 (CTS) 易感性增加有关.
以前的研究表明,机械和组织学变化有助于这种风险.

研究的目的:

为了研究TCL的与年龄相关的机械特性.
检查TCL和中枢神经中与年龄相关的组织学变化.

主要方法:

分析了来自50具尸体 (40-93岁) 的100个TCL标本.
在现场的机械测试 (刚性,弹性,放松,爬行) 使用MyotonPRO.
组织学分析 (马森三色素,SEM) 和与年龄的相关性.

主要成果:

TCL 显示年龄相关的硬度增加,弹性降低,放松时间和爬行.
组织学显示,较旧的TCL中纤维细胞密度降低,原不组织,纤维细胞间矩阵增加.
来自老年尸体的中枢神经表现出周围连接组织较薄,骨髓膜减少.

结论:

随着年龄的增长,TCL会变硬,结构也会失调.
中间神经的退行性变化伴随着衰老.
这些与年龄相关的变化可能会增加老年人手掌道综合征的风险.

关键词:

衰老的衰老衰老的衰老手管道中的手腕道.机械性质机械性质中间神经的神经.横向的手腕带横向的手腕带

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