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青少年的胰腺固体伪皮质瘤:一个不常见的发现

Ana Sofia Nunes¹, Sofia Martinho², Luciana Abelha³

¹Department of Paediatrics, Unidade Local de Saúde de Braga, Braga, PRT.

|March 2, 2026

概括

固体伪毛囊瘤 (SPN) 是儿童罕见的胰腺瘤. 手术切除SPN提供了很好的预后,免疫组织化学对于诊断至关重要.

科学领域:

儿科瘤学儿科瘤学
手术病理学手术病理学
胃肠道手术胃肠道手术

背景情况:

固体伪毛囊瘤 (SPN) 是一种罕见的胰腺瘤,具有低恶性潜力,主要影响青少年女性.
SPN通常是偶然诊断的,但可以出现诸如腹痛,发烧,吐和厌食症等症状.

研究的目的:

报告一个SPN病例在一个11岁的女孩呈现急性腹部症状.
突出诊断方面的考虑和成功管理儿科SPN.

主要方法:

一个11岁的女性患有胰腺质量的案例报告.
诊断成像包括CT和MRI.
laparoscopic 脏保护的远部胰腺切除术.
针对瘤标记物的免疫组织化学染色.

主要成果:

确定了一个大而异质的胰腺尾部质量.
瘤标志物不显著;患者最初接受了抗生素治疗.
组织病理学证实了SPN,对β-catenin,CD56,cyclin D1和synaptophysin进行了阳性染色.
没有发现淋巴结转移 (pT3N0M0).

结论:

在儿童胰腺质量的差异诊断中应考虑SPN.
手术切除为儿科SPN提供了很好的预后.
免疫组织化学,特别是β-catenin染色,对于准确的诊断至关重要.

关键词:

儿童和青少年的孩子和青少年.儿科放射学儿科放射学儿科外科手术儿科外科手术在胰腺瘤中.固体伪毛囊性瘤发生.

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