结肠直肠癌的统计,2026年
Rebecca L Siegel1, Nikita Sandeep Wagle1, Jessica Star1
1Surveillance, Prevention, and Health Services Research, American Cancer Society, Atlanta, Georgia, USA.
CA: a cancer journal for clinicians
|March 2, 2026
概括
大肠直肠癌 (CRC) 的发病率和死亡率在65岁以下的成年人中正在上升,特别是年轻人. 这一趋势需要对病因进行紧急研究,并改进对这一人口群体的早期检测策略.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 结肠直肠癌 (CRC) 是美国癌症死亡的主要原因,特别是在50岁以下的成年人中.
- 最近的趋势显示,老年人中CRC发病率正在下降,但年轻人群中的CRC发病率正在上升.
- 结直肠癌的发病率有所上升,特别是在年轻年龄组.
研究的目的:
- 分析美国不同年龄组结直肠癌发病率和死亡率的当前趋势.
- 为了突出在65岁以下的成年人中与65岁及以上的成年人中观察到的对比模式.
- 强调对年轻的CRC患者进行进一步研究和改善临床和公共卫生策略的需要.
主要方法:
- 利用了基于人口的癌症登记处的发病率数据和国家卫生统计中心的死亡率数据.
- 分析了2013-2022年不同年龄人口的CRC发病率的年度百分比变化.
- 检查诊断阶段和死亡率趋势,包括特定人群中的差异.
主要成果:
- 整体CRC发病率每年都在下降,主要原因是65岁以上成年人数的显著下降.
- 相反,CRC发病率在20-49岁 (3%) 和50-64岁 (0.4%) 的成年人中每年增加,其中偏远结肠和直肠瘤占主导地位.
- 自2004年以来,50岁以下的成年人死亡率增加了,自2019年以来,50-64岁年龄组的死亡率增加了,与老年人死亡率的下降形成鲜明对比.
结论:
- 结肠直肠癌的发病率和死亡率在65岁以下的成年人中正在增加,这在生命之初的个人中是一个令人担忧的趋势.
- 较年轻发病的CRC的增加,特别是晚期的CRC,需要紧急进行病因学调查.
- 缓解策略应侧重于早期诊断,提高公众对症状的认识,并解决年轻患者的特殊需求,包括生育能力和性健康保护.
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