一个长达13年的高等医疗中心在老年人群中患有传染性角膜炎的经验
Emre Karahan1, Ozlem Barut Selver1, Sohret Aydemir2
1Department of Ophthalmology, Ege University, 35100, Izmir, Turkey.
International ophthalmology
|March 2, 2026
概括
在患有传染性角膜炎的老年患者中,Streptococcus pneumoniae是最常见的病原体,与其他研究不同. 干眼和免疫抑制与糟糕的结果有关,这表明有针对性的治疗是至关重要的.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 老年病的医生 老年病的医生
背景情况:
- 传染性角膜炎对视力构成重大威胁,特别是在老年人群中.
- 了解这一人口群中的特定病原体和风险因素对于有效管理至关重要.
研究的目的:
- 为了分类,描述临床表现,并评估60岁及以上患者感染性角膜炎的治疗结果.
- 确定常见的病原体和相关的并发症,影响老年人感染性角膜炎病例的结果.
主要方法:
- 在2012年1月至2025年1月期间,对317名被诊断患有传染性角膜炎的患者 (≥60岁) 进行了回顾性单中心分析.
- 评估微生物培养,临床过程,并发病,治疗和视力敏度的结果.
主要成果:
- 肺炎链球菌是最常见的病原体 (29.7%),与其他报告形成鲜明对比.
- 平均最佳校正视敏度在治疗后显著改善 (p < 0.001).
- 眼睛干燥 (43.8%) 和全身免疫抑制 (36.9%) 是普遍存在的并发症,与较差的结果相关;注意到复发和需要角膜移植或内脏切除.
结论:
- 老年人的传染性角膜炎可能主要是由肺炎菌引起的,这表明区域差异.
- 干眼和全身免疫抑制是这种人群中不良结果的重要风险因素.
- 针对这些并发症的个性化治疗策略对于改善视觉结果至关重要.
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