在乳腺癌管理中使用补充和替代医学
Oluwaseun F Ayoade1, Giorgio Caturegli1, Maureen E Canavan2
1Division of Thoracic Surgery, Department of Surgery, Yale University School of Medicine, New Haven, Connecticut.
JAMA network open
|March 2, 2026
概括
在乳腺癌患者中使用补充和替代医学 (CAM) 不常见. 使用CAM而不是传统治疗的患者的生存率降低,突出了基于证据的护理的重要性.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 乳腺癌的治疗已经取得了进展,减少了发病率和改善了生存率.
- 尽管取得了进展,但一些患者选择了补充和替代医学 (CAM).
研究的目的:
- 研究CAM使用与乳腺癌患者的生存结果之间的关联.
- 为了比较接受传统治疗,CAM或不接受治疗的患者的生存率.
主要方法:
- 一项队列研究分析了来自国家癌症数据库 (NCDB) 的数据,用于在2011-2021年期间诊断出的女性乳腺癌患者.
- 使用Kaplan-Meier分析和Cox比例危险模型来比较生存时间.
- 共同变量包括年龄,种族,并发症,保险,设施类型,地区,诊断年,癌症阶段和收入.
主要成果:
- 使用CAM并不常见 (单独:<0.1%;组合:<0.1%).
- 与传统疗法相比,单独使用CAM或不使用CAM的患者的死亡风险明显更高.
- 将CAM与传统疗法结合使用与较高的死亡率 (AHR, 1.45) 和较少使用内分泌疗法和辐射疗法有关.
结论:
- 使用CAM而不是传统的乳腺癌疗法与生存率降低有关.
- 在乳腺癌中使用CAM值得进一步调查,因为它与较差的结果有关.
- 基于证据的治疗对于乳腺癌患者的最佳生存至关重要.
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