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Updated: May 5, 2026

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
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Published on: July 25, 2020

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一个新辅助性卡博桑提尼布的第一阶段研究,与极端肉瘤的辐射疗法结合

Hannah R Abrams1,2, Elizabeth T Loggers1,2, Michael J Wagner1,3

  • 1Clinical Research Division.

American journal of clinical oncology
|March 2, 2026
PubMed
概括

这一第一阶段试验发现,同步使用卡博桑提尼布和放射治疗对于四肢软组织肉瘤 (STS) 是安全的. 推的第二期剂量 (RP2D) 为60毫克卡博桑提尼布,没有观察到该组合的剂量限制性毒性.

关键词:
多激酶抑制剂的使用这是一种新辅助剂.第一个阶段I阶段.肉瘤 肉瘤是一种肉瘤.软组织肉瘤软组织肉瘤

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