通过代谢工程推进活细胞中的遗传密码扩展

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Updated: Mar 4, 2026

Optimizing the Genetic Incorporation of Chemical Probes into GPCRs for Photo-crosslinking Mapping and Bioorthogonal Chemistry in Live Mammalian Cells
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Optimizing the Genetic Incorporation of Chemical Probes into GPCRs for Photo-crosslinking Mapping and Bioorthogonal Chemistry in Live Mammalian Cells

Published on: April 9, 2018

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D'Jana R Wyllis1, Saloni P Gupta1, Shelby R Anderson1

  • 1Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware, USA;

Annual review of chemical and biomolecular engineering
|March 2, 2026
PubMed
概括

遗传密码扩展 (GCE) 能够创建具有新型构建块的蛋白质,即非标准氨基酸 (nsAAs). nsAAs的生物合成克服了化学合成的局限性,推进了蛋白质工程和合成生物学.

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