影响脏体积和功能的因素在 laparoscopic 部分瘤切除术后:长期3D体积分析
Onur Kalaycı1, Ender Özden2, Murat Gülşen2
1Department of Urology, Samsun City Hospital, Samsun, Turkey.
糖尿病严重影响部分切除术后的长期功能,超过早期保存的体积. 像外科手术技术这样的可修改因素可以改善对细胞体积的保存,以获得更好的脏结果.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 手术瘤学手术瘤学
背景情况:
- 腹腔镜部分切除术 (LPN) 是对脏瘤的标准治疗方法.
- 在LPN后评估长期体积和功能对于患者管理至关重要.
- 3D建模为外科评估提供了先进的可视化.
研究的目的:
- 用3D建模评估LPN后体积和功能的长期变化.
- 为了确定功能下降和LPN后对瘤体积损失的关键预测因素.
主要方法:
- 187名接受LPN治疗的患者的回顾性分析 (2012年10月 - 2023年1月).
- 术前和术后的横截面成像与至少1年的随访.
- 用于体积重建的3D切片软件.
主要成果:
- 平均膜体积从手术前的168.87cm3减少到手术后5年后的137.6cm3.
- 在同一时期,估计的淋巴膜过率 (eGFR) 从90.6降至75.9mL/min/1.73m2.
- 预测eGFR下降的预测因素包括对酶体体积损失,年龄,女性性别,糖尿病和瘤接触面积.
结论:
- 虽然保持体积是早期的关键,但糖尿病是LPN后功能的主要长期决定因素.
- 手术技术和手术时间会影响对酶体体积的保存.
- 核化可能会改善对酶体的保存,而不会影响瘤的结果.
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