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双X射线吸收仪在年轻人的腿长度
Jack S Dooley1, Lance C Liu1, Bonny Donzella2
1Laboratory of Integrative Human Physiology, University of Minnesota, Minneapolis, MN 55455, USA.
概括
双X射线吸收计 (DXA) 提供了精确的腿长度测量,与传统方法高度相关. 这种技术可以可靠地评估青少年腿长和心脏代谢健康之间的关联.
科学领域:
- 人类测量学 人类测量学.
- 放射性成像学成像学
- 青少年健康 青少年健康
背景情况:
- 腿的长度是心血管疾病,代谢疾病和2型糖尿病风险的已知预测因素.
- 传统的腿长度测量包括从站立的腿长度减去坐着的.
- 双X射线吸收计 (DXA) 为确定腿部长度提供了一个潜在的替代方法.
研究的目的:
- 检查DXA衍生腿长 (DXA-LL) 和传统衍生腿长 (T-LL) 之间的关系.
- 确定DXA-LL和T-LL测量是否产生与心脏代谢健康和骨密度相似的关联.
- 验证DXA作为青少年腿长度测量的准确工具.
主要方法:
- 140名青少年 (74名出生,66名先前住院) 接受了传统的腿长度测量和全身DXA扫描.
- 根据DXA推导的腿长度 (DXA-LL) 使用定制感兴趣的区域进行计算.
- 统计分析检查了DXA-LL和T-LL之间的相关性,以及它们与健康标志物的关联.
主要成果:
- 虽然DXA-LL和T-LL测量高度相关 (r=0.96,p<0.001),但DXA-LL估计略低一些.
- 在对年龄和性别进行控制后,与以前住院的青少年相比,出生后的青少年表现出更长的DXA-LL.
- 较长的DXA-LL与较低的葡萄糖,胆固醇,甘油三,HDL和骨密度增加有关,类似于T-LL的发现.
结论:
- 由DXA衍生的腿长是准确可靠的测量工具.
- DXA提供了一种有效的方法来评估腿的长度及其与青少年心脏代谢健康和骨密度的关系.
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