实时脑电脑接口控制行走的外骨与双边感官反
Jeffrey Lim1, Po T Wang1, Won Joon Sohn2
1Department of Biomedical Engineering, University of California, Irvine (UCI), Irvine, CA, USA.
Brain stimulation
|March 2, 2026
概括
这项研究展示了一种双向大脑-计算机接口 (BDBCI),允许实时大脑控制的行走和人工腿感觉. 这项技术为脊髓损伤 (SCI) 患者恢复行走提供了新的途径.
科学领域:
- 神经科学是一个神经科学.
- 生物医学工程 生物医学工程
- 康复技术 康复技术 康复技术
背景情况:
- 脊髓损伤 (SCI) 严重影响行走,需要先进的辅助技术.
- 目前用于步行的脑电脑接口 (BCI) 是单向的,缺乏至关重要的感官反.
- 恢复运动控制和感官感知对于功能恢复至关重要.
研究的目的:
- 演示一种双向脑-计算机接口 (BDBCI),用于同时实时脑控制的行走和人工腿的感觉.
- 为了研究使用电刺激的感觉皮层的人工腿感觉.
- 确定嵌入式BDBCI系统的可行性,以恢复行走功能.
主要方法:
- 招募了患有的患者,双边半球间皮下电皮录像 (ECoG) 植入物.
- 使用运动映射用于腿部运动皮层解码步行意图.
- 在体感皮质中使用感官刺激映射用于人工腿的感知.
- 开发了一个定制的嵌入式BDBCI来控制机器人步行外骨架 (RGE) 并提供感官反.
主要成果:
- 在BDBCI控制的RGE操作中实现了高解码性能 (ρ = 0.92 ± 0.04).
- 在盲目计步任务中高准确度 (92.8%) 验证了双边腿的感知.
- 证实刺激工件不会影响解码性能;没有报道任何不良事件.
结论:
- 建立了嵌入式BDBCI系统的可行性,以恢复运动控制和人为的行走感觉.
- 证明利用半球间腿部传感运动皮层是安全的,并改善解码.
- 为将BDBCI技术转化为SCI患者的完全可植入系统提供了基础.
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