在三个北欧队列中,孕期的海洋n-3长链多不和脂肪酸摄入量和早期生命感染风险:HEDIMED联盟研究
Aino K Rantala1, Leena Hakola2, Nicklas Brustad3
1Department of Chronic Diseases, Norwegian Institute of Public Health, Oslo, Norway; Center for Environmental and Respiratory Health Research (CERH), Research Unit of Population Health, University of Oulu, Oulu, Finland.
The Journal of nutrition
|March 2, 2026
概括
怀孕期间母亲摄入的omega-3脂肪酸并没有持续降低幼儿感染风险. 虽然观察到对上呼吸道感染和胃肠炎的一些益处,但总体证据仍然不确.
科学领域:
- 免疫学和公共卫生
- 营养科学 营养科学
- 儿科健康 儿科健康
背景情况:
- 欧米茄-3长链多不和脂肪酸 (n-3 LCPUFA) 具有抗炎性质.
- 这些特性可能调节与免疫媒介疾病相关的免疫反应.
研究的目的:
- 检查孕妇摄入的n-3 LCPUFA与儿童早期感染的发生率之间的关联.
- 研究omega-3脂肪酸对儿童健康的潜在保护作用.
主要方法:
- 来自三个大型北欧队列 (MoBa,DIPP,COPSAC2010) 的数据分析,涉及超过77,000对母婴.
- 通过问卷,抗体水平和病毒PCR评估的感染发病率.
- 使用食物频率问卷和随机鱼油干预评估的母体n-3 LCPUFA摄入量.
主要成果:
- 在较高的n-3 LCPUFA摄入量和整体呼吸道感染减少之间没有发现显著的关联.
- 在一个队列 (MoBa) 中增加n-3 LCPUFA摄入量时,观察到上呼吸道感染和胃肠炎的风险降低.
- 在其他队列中,没有发现有关coxsackievirus感染或特定呼吸道病原体的显著影响.
结论:
- 这项研究没有发现一致的证据支持早儿感染的减少与更高的孕产妇在怀孕期间的n-3 LCPUFA摄入.
- 可能需要进一步的研究来澄清欧米茄-3脂肪酸在儿童感染预防中的作用.
关键词:
这是COPSAC COPSAC.迪普普 (DIPP) 是一个非常有价值的公司.摩巴巴是什么意思 摩巴巴是什么意思童年的童年 童年的童年队列研究是一项队列研究.饮食中的脂肪酸 食中的脂肪酸感染 感染 感染怀孕 怀孕 怀孕 怀孕 怀孕更多相关视频
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