小细胞肺癌通过活跃的细胞外ATP运输建立了新陈代谢自机制

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Updated: Mar 4, 2026

Fluorescence Microscopy for ATP Internalization Mediated by Macropinocytosis in Human Tumor Cells and Tumor-xenografted Mice
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Fluorescence Microscopy for ATP Internalization Mediated by Macropinocytosis in Human Tumor Cells and Tumor-xenografted Mice

Published on: June 30, 2021

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Takeshi Tsuruda1,2, Manabu Kodama1, Keiichi I Nakayama1,2

  • 1Anticancer Strategies Laboratory, Advanced Research Initiative, Institute of Science Tokyo, Tokyo, Japan.

Cancer science
|March 2, 2026
PubMed
概括

小细胞肺癌细胞通过PANX1通道释放ATP,以促进扩散. 准这种泛素1 (PANX1) 和P2RX7受体通路可能提供新的SCLC治疗方法.

关键词:
腺三酸盐 (ATP) 是一种链接离子通道7 (P2RX7)代谢性自闭症的自闭症代谢泛素1 (PANX1) 的使用纯能受体 P2X 纯能受体小细胞肺癌 (SCLC) 是一种癌症.

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