期待调节了中脑对甜味味道的快乐体验和中脑反应
Elena Mainetto1,2, Margaret L Westwater1,3, Hisham Ziauddeen1,4
1Department of Psychiatry, University of Cambridge, Herchel Smith Building, Addenbrooke's Hospital, Cambridge CB2 0SZ, UK.
概括
期望显著影响大脑如何感知糖和非营养甜味剂的甜味. 相信饮料是糖会增加对人工甜味剂的奖励反应,影响食物选择.
科学领域:
- 神经科学是一个神经科学.
- 感官科学 感官科学
- 行为科学 行为科学
背景情况:
- 非营养甜味剂 (NNS) 是通过减少卡路里摄入量来控制体重的糖替代品.
- 目前尚不清楚糖和NNS是否引起了不同的大脑反应,或者期望是否调节了这些神经信号.
- 了解这些差异对于饮食干预和食物选择行为至关重要.
研究的目的:
- 为了调查糖和NNS是否引起不同的耳感官大脑反应.
- 为了确定神经对甜味的反应是否受到预期的调制.
- 将这些发现与食物选择行为和饮食干预联系起来.
主要方法:
- 对27名健康成年人进行fMRI扫描,他们对糖和NNS的感知类似.
- 在概率和确定性期望范式下,服用糖和人工甜味饮料.
- 操纵参与者对味道传递的期望,以评估神经和行为反应.
主要成果:
- 参与者区分糖和NNS的准确性取决于预期.
- 期望显著改变了人们对糖和NNS的愉悦感.
- 当感官信息不可靠时,对糖的期望会增加中脑对NNS的反应 (决定性任务).
结论:
- 预期在甜味的行为和神经编码中起着至关重要的作用,特别是在不可靠的感官输入的情况下.
- 对糖的期望增强了非热量甜味剂的主观价值,可能是由于风味-营养条件.
- 这些发现表明,糖的有益作用可能超过NNS,影响食物选择行为.
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