度增强调节的性粘合 皮豆类皮像多糖在唾液粘液层内的多糖
Xinyu Zhang1, Weixiang Sun2, Peiyao Zhao1
1Laboratory of Food Proteins and Colloids, School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, P. R. China.
Journal of agricultural and food chemistry
|March 2, 2026
概括
大豆聚糖 (SHP) 分数通过影响离子 (Na+) 扩散和保留在唾液中来调节度感知. 酸性SHP (SHP-A) 通过改善粘膜粘合,比中性SHP (SHP-N) 更有效地提高盐度.
科学领域:
- 食品科学与技术 食品科学与技术
- 生物化学 生物化学
- 材料科学 是一种材料科学.
背景情况:
- 度感知受到唾液层中离子 (Na+) 行为的影响.
- 粘粘性多糖会影响Na+的扩散和保留,影响度.
- 由于其复杂的结构,大豆聚糖 (SHP) 的盐度增强机制尚未完全理解.
研究的目的:
- 调查不同大豆多糖 (SHP) 分数在调节度感知中的作用.
- 阐明SHP对离子 (Na+) 扩散和保留在唾液中的作用背后的机制.
- 确定SHP的关键结构特征,负责盐度增强和粘膜粘合.
主要方法:
- 将SHP分解成中性 (SHP-N,半纤维素) 和酸性 (SHP-A,RG-I丰富的pectin) 的组成部分.
- 在模拟的唾液层中研究Na+和SHP粘结.
- 分析SHP分量的对Na+扩散和保留动态的影响.
主要成果:
- 酸性SHP (SHP-A) 与中性SHP (SHP-N) 相比,显示出更强的度增强效应.
- SHP-A加速了Na+扩散并延长了其保留时间,主要是由静电选和疏水相互作用驱动的.
- 强烈的SHP-A-mucin相互作用,由RG-I区域介导,影响了Na+吸附-脱附动态.
结论:
- 像SHP-A这样的酸性多糖体内的特定结构域对于增强度感知至关重要.
- 由静电和疏水力驱动的粘膜粘合,在SHP的盐度增强机制中起着关键作用.
- 了解多糖的结构-功能关系可以为食品成分的设计提供信息,以调节味道.
相关概念视频
Gustation
43.5K
Gustation is a chemical sense that, along with olfaction (smell), contributes to our perception of taste. It starts with the activation of receptors by chemical compounds (tastants) dissolved in the saliva. The saliva and filiform papillae on the tongue distribute the tastants and increase their exposure to the taste receptors.
43.5K
Glycosaminoglycans
6.4K
Glycosaminoglycans (GAGs), also known as mucopolysaccharides, are long and linear polymers comprising of specific repeating disaccharides - the amino sugar that can be N-acetylglucosamine or N-acetylgalactosamine, and a uronic acid that is usually glucuronic acid or iduronic acid.
GAGS are found in the extracellular matrix of vertebrates, invertebrates, and bacteria. Due to their polar nature they attract water, and serve as excellent lubricants or shock absorbers in an animal body.
Hyaluronic...
GAGS are found in the extracellular matrix of vertebrates, invertebrates, and bacteria. Due to their polar nature they attract water, and serve as excellent lubricants or shock absorbers in an animal body.
Hyaluronic...
6.4K
The Physiology of Taste
6.8K
The perception of a salty flavor is facilitated by sodium ions within the oral salivary fluid. Upon consumption of a salty substance, salt crystals disassemble, leading to the liberation of its constituents—Na+ and Cl- ions. These ions subsequently dissolve into the salivary fluid present in the oral cavity. The external environment of the gustatory cells experiences an elevation in Na+ concentration, thereby establishing a potent concentration gradient. This gradient propels the...
6.8K
Salivary Glands and Saliva
3.1K
The salivary glands, of which there are three pairs known as the parotid, submandibular, and sublingual glands, play a crucial role in maintaining oral health and initiating the digestive process. Positioned near the ears, beneath the masseter muscle, the parotid glands secrete saliva into the oral cavity through the parotid duct of Stensen. Meanwhile, the submandibular glands, located on the floor of the mouth, secrete saliva through channels named submandibular ducts. The sublingual glands,...
3.1K
Bioavailability Enhancement: Drug Solubility Enhancement
499
Bioavailability is a critical factor in determining a drug's effectiveness. It refers to the proportion of a drug that enters the circulation when introduced into the body and is, as a result, able to have an active effect. Enhancing bioavailability is essential for drugs with poor solubility, as it can significantly impact their therapeutic efficacy. Various methods are employed to increase the solubility of drugs, thereby enhancing their bioavailability.Micronization and nanonization are...
499
Bioavailability Enhancement: Drug Permeability Enhancement
352
After oral administration, poor permeability often limits the rate at which drugs are absorbed through the intestinal epithelium. Enhancing drug permeability is crucial for effective therapy, and several strategies have been developed to overcome this challenge.One effective strategy involves the use of lipid-based formulations. These formulations enhance dissolution and solubility, targeting physiological mechanisms to increase drug absorption. This includes stimulating bile salt secretion,...
352


