临床特征与内源性内炎的预后不佳相关:来自5年后期研究的新见解
Ru Jian Jonathan Teoh1, Muhammad Irfan Abdul Jalal2, Nor Azita Ahmad Tarmidzi1
1Department of Ophthalmology, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia.
Ocular immunology and inflammation
|March 2, 2026
概括
内源性内眼炎 (EE) 是一种严重的眼部感染. 眼皮胀,眼睛疼痛和Klebsiella肺炎感染表明视力和地球生存的预后不佳.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 微生物学 微生物学
背景情况:
- 内源性内眼炎 (EE) 是一种罕见但严重的眼内感染,威胁视力.
- 糖尿病是一种与EE相关的重要并发症,影响了本研究中87.9%的患者.
- 在血液和玻璃体培养中,Klebsiella pneumoniae被确定为主要的病原体.
研究的目的:
- 评估内源性内耳炎 (EE) 的临床特征,危险因素和微生物谱.
- 为了确定马来西亚一家三级医院EE的视觉和解剖结果.
- 确定影响EE患者视力敏度和全球生存的预后因素.
主要方法:
- 对2020年至2024年间被诊断患有EE的患者的医疗记录进行了回顾性审查.
- 包括来自33名患者的41只眼睛.
- 对临床数据,微生物学结果和患者结果的分析,包括视力敏度和内脏切除的需要.
主要成果:
- 最常见的病原体是Klebsiella pneumoniae (18.2%的血液,22.0%的玻璃体).
- 视力不佳的结果与眼胀 (aOR=30.66) 和Klebsiella肺炎感染 (aOR=27.69) 有关.
- 球体损失与眼睛疼痛 (aHR=3.78) 和Klebsiella肺炎感染 (aHR=7.15) 有关,第一年球体生存率为66.2%.
结论:
- 胀的眼和眼睛疼痛是内源性内耳炎 (EE) 预后不佳的关键指标.
- 克莱布西拉肺炎感染仍然是视觉结果和地球生存的显著负面预测因素.
- 早期识别这些临床症状对于及时干预至关重要,以保护EE的视力和眼部完整性.
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