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Updated: Jun 9, 2026

A Microphysiological System to Study Leukocyte-Endothelial Cell Interaction during Inflammation
12:55

A Microphysiological System to Study Leukocyte-Endothelial Cell Interaction during Inflammation

Published on: December 9, 2021

树突细胞中的血红素受体激活通过抑制S100a8/a9介导的中性粒细胞招募来缓解败血症

Ronglu Du1, Ting Pan1, Yuhan Wang1

  • 1Department of Pharmacology, Tianjin Key Laboratory of Inflammatory Biology, Center for Cardiovascular Diseases, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, State Key Laboratory of Experimental Hematology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.

Signal transduction and targeted therapy
|March 2, 2026
PubMed
概括

树突细胞 (DC) 血红素A2受体 (TP) 缺陷通过增加中性粒细胞的招募来加剧败血症. 在DC中激活TP可以防止败血症引起的肺损伤,揭示TP作为潜在的败血症治疗标.

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