在2型糖尿病中进行放射形态测量和基于纹理的下骨评估:与维生素D,骨素和血糖控制相关 - - 一项分析横截面研究
A Benjamin Rajasekar1, C L Krithika2, Anuradha Ganesan1
1Department of Oral Medicine and Radiology,SRM Dental College, Ramapuram, Bharathi Salai, Chennai, Tamil Nadu, 600089, India.
Scientific reports
|March 2, 2026
概括
2型糖尿病 (T2DM) 显著降低下骨质量,影响皮层和椎结构. 全景射线图可以帮助查糖尿病患者的骨变化.
科学领域:
- 口腔和面放射学 口腔和面放射学
- 内分泌学 在内分泌学.
- 骨的新陈代谢 骨的新陈代谢
背景情况:
- 2型糖尿病 (T2DM) 是一种影响骨代谢的全身性疾病.
- 骨质量对口腔健康至关重要,可以反映系统性骨健康.
- 现有的研究缺乏综合分析,将生物化学标记与T2DM相关下巴变化的高级成像指数集成在一起.
研究的目的:
- 评估T2DM与下骨质量之间的关联.
- 为了全面评估,将生物化学标记与放射形态测量和基于纹理的指数集成在一起.
- 为了确定T2DM是否影响下骨质量,无论年龄,性别和血糖控制.
主要方法:
- 横截面研究比较了四组:健康的男性,健康的女性,糖尿病男性和糖尿病女性.
- 生物化学标志物的评估 (维生素D,骨素).
- 使用下骨质量的量化 精神指数 (MI),周骨指数 (PMI),下皮质指数 (MCI),碎形维度,状支架分析和灰色水平共发生矩阵 (GLCM) 特性.
- 统计分析包括克鲁斯卡尔-瓦利斯,奇平方,斯皮尔曼相关性和多变量回归.
主要成果:
- 患有糖尿病的参与者表现出较低的维生素D和骨质素含量,降低的MI,PMI和增加的MCI,表明皮质稀薄和多孔性.
- 碎形尺寸和状支架参数的恶化被注意到,特别是在糖尿病男性中.
- 糖尿病状况独立地与皮质稀薄和较高的MCI相关;HbA1c与骨素减少相关.
结论:
- T2DM与下巴皮层和椎骨质量的临床显著降低有关.
- 传统的放射形度指数 (MI,PMI,MCI) 是可靠的,并且在临床上可用于评估T2DM相关的下变化.
- 全景射线图可以作为辅助工具,用于糖尿病人群的骨变化的机会性查.
关键词:
骨密度 骨密度 骨密度 骨密度糖尿病是一种糖尿病.碎形法则是什么? 碎形法则是什么?整形术术术术 (Orthopantomography) 是一个术术.骨质素是一种骨质素.骨质疏松症是一种骨质疏松症.维生素D 维生素D是一种维生素.更多相关视频
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