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基于近视的超广场光学连贯断层扫描的虚拟全眼模型的构建

Xiangcheng Tang¹, Na Luo¹, Caiyi Chen¹

¹Shenzhen Eye Hospital, Shenzhen Eye Medical Center, Southern Medical University, Shenzhen, China.

NPJ digital medicine

|March 2, 2026

概括

一个新的虚拟整眼模型 (CET-1),用光学连贯性断层扫描创建,为MRI提供了一种方便的替代方案,用于评估眼部形态. 这种数字双眼模型准确地跟踪近视的进展,并有助于个性化治疗策略.

科学领域:

眼科医生眼科眼科
医疗成像医学成像
生物医学工程生物医学工程

背景情况:

磁共振成像 (MRI) 对评估眼睛形态提出了挑战.
准确评估眼睛形状对于理解视力状况至关重要,如近视.

研究的目的:

开发和验证一种新的三维虚拟整眼模型 (CET-1),使用超广场扫描源光学连贯断层扫描.
为了比较CET-1模型与MRI的准确性,以评估不同程度近视的眼睛形态.

主要方法:

开发CET-1虚拟眼睛模型,使用超广场扫描源光学连贯性断层扫描.
验证CET-1模型与80只眼睛的MRI数据相比,来自40个不同近视水平的个体.
对眼睛参数的分析,包括后部段高斯曲率和前部段度量,与近视相关.

主要成果:

该CET-1模型在广泛的轴长度 (22.1932.56毫米) 中与MRI显示出高一致性.
模型之间的平均点到表面距离为0.0183±0.0025标准化单位 (439.57±59.87μm).
在近视和正常组之间观察到眼睛参数的显著差异 (P <0.05).

结论:

CET-1模型是创建数字双眼模型的简单有效工具.
这项技术有助于对近视的发展和进展进行定量分析和监测.
该CET-1模型支持优化治疗策略,并推进个性化眼科.

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