Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Hierarchy of Motor Control01:18

Hierarchy of Motor Control

6.5K
The hierarchy of motor control refers to the different levels of organization and processing involved in controlling movement in the body. These levels range from higher cortical areas involved in planning and decision-making to lower spinal cord reflexes that respond automatically to external stimuli.
6.5K
Direct Motor Pathways01:11

Direct Motor Pathways

4.9K
The direct motor pathways, also known as the pyramidal tracts, are a group of neural pathways that originate in the brain and descend through the spinal cord. They control the voluntary movement of the body. There are two major direct motor pathways: the corticospinal and the corticobulbar tracts.
The corticospinal tract is responsible for the voluntary movement of the limbs and trunk. It originates in the cerebral cortex of the brain and descends through the cerebrum's internal capsule and...
4.9K
Indirect Motor Pathways01:22

Indirect Motor Pathways

3.7K
The indirect motor or extrapyramidal pathways originate in the brainstem, the lower portion of the brain that connects it to the spinal cord. They consist of several distinct tracts, each with specialized functions. The four main tracts of the indirect motor pathways are the vestibulospinal tract, the reticulospinal tract, the tectospinal tract, and the rubrospinal tract.
The vestibulospinal tract originates in the vestibular nuclei of the brainstem. The vestibular system detects changes in...
3.7K
Generation of Action Potential in Skeletal Muscles01:24

Generation of Action Potential in Skeletal Muscles

9.7K
Every cell in the body maintains a membrane potential due to an uneven distribution of positive and negative charges across its plasma membrane. The membrane potential is measured in millivolts and quantifies the difference in charge across the membrane.
Like neurons, muscle cells are also regarded as excitable due to their capacity to change in response to stimuli, primarily due to voltage-gated ion channels embedded in their plasma membranes, which get activated by alterations in the...
9.7K
Muscles of the Leg that Move the Foot and Toes01:28

Muscles of the Leg that Move the Foot and Toes

4.4K
The human leg comprises an intricate system of muscles that facilitate the movement of feet and toes. Within this system, the muscles are categorized into the anterior, lateral, and posterior compartments, each with a unique set of muscles carrying out specific functions.
Anterior Compartment
The anterior compartment includes muscles that contribute to the dorsiflexion of the foot. This compartment houses the tibialis anterior, extensor hallucis longus, and extensor digitorum longus muscles....
4.4K
Design Example: Frog Muscle Response01:14

Design Example: Frog Muscle Response

637
A student is tasked to work on an intriguing experiment involving an RL (Resistor-Inductor) circuit to study the muscle response of a frog's leg to electrical stimulation. The RL circuit plays a crucial role in this experiment, providing the means to control and measure the electrical impulses that trigger muscle contraction.
When the switch connecting the RL circuit is closed, a brief muscle contraction is observed. This is because, at a steady state, the inductor acts like a short...
637

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Persistent interferon signaling causes sensory neuron plasticity and pain before and during arthritis.

Nature neuroscience·2026
Same author

Separate brainstem circuits for fast steering and slow exploratory turns.

Nature communications·2025
Same author

Molecular blueprints for spinal circuit modules controlling locomotor speed in zebrafish.

Nature neuroscience·2023
Same author

A specialized spinal circuit for command amplification and directionality during escape behavior.

Proceedings of the National Academy of Sciences of the United States of America·2021
Same author

Functional diversity of excitatory commissural interneurons in adult zebrafish.

eLife·2016

相关实验视频

Updated: Mar 4, 2026

Studying the Neural Basis of Adaptive Locomotor Behavior in Insects
10:19

Studying the Neural Basis of Adaptive Locomotor Behavior in Insects

Published on: April 13, 2011

13.3K

重新定义脊椎动物运动的中央模式生成器.

Abdeljabbar El Manira1

  • 1Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden. abdel.elmanira@ki.se.

Nature reviews. Neuroscience
|March 2, 2026
PubMed
概括

中央模式生成器 (CPG) 被重新定义为动态的模块化系统,而不仅仅是节奏生成器. 斑马鱼的研究揭示了由感官反影响的脊椎动物运动的适应性,多层控制.

科学领域:

  • 神经科学是一个神经科学.
  • 动物学 动物学
  • 生物力学 生物力学

背景情况:

  • 中央模式生成器 (CPG) 概念对于理解脊椎动物的运动至关重要.
  • 最近的斑马鱼研究挑战了CPG作为简单的节奏生成器的经典观点.

研究的目的:

  • 将CPG重新定义为基于斑马鱼模型的动态,模块化和混合感应运动系统.
  • 为了比较斑马鱼和哺乳动物之间的保存和分离的CGG原则.

主要方法:

  • 利用斑马鱼作为电路级神经科学的主要模型系统.
  • 将斑马鱼的发现与哺乳动物的保存和分离原则进行比较.

主要成果:

  • CPG由速度特定的模块组成,通过"变速"机制激活.
  • 大脑干电路作为分层控制器来启动和调制运动.
  • 运动神经元和自身受体是影响节奏和协调的不可分割的CPG组件.

结论:

  • 脊椎动物的CPG是一种高度适应性的多层控制系统,通过感觉反和下降输入进行调整.
  • 斑马鱼研究为解码适应性运动提供了路线图,并为陆地脊椎动物提供了可测试的假设.

更多相关视频

Kinematics and Ground Reaction Force Determination: A Demonstration Quantifying Locomotor Abilities of Young Adult, Middle-aged, and Geriatric Rats
10:28

Kinematics and Ground Reaction Force Determination: A Demonstration Quantifying Locomotor Abilities of Young Adult, Middle-aged, and Geriatric Rats

Published on: February 22, 2011

20.2K
Zebrafish In Situ Spinal Cord Preparation for Electrophysiological Recordings from Spinal Sensory and Motor Neurons
08:24

Zebrafish In Situ Spinal Cord Preparation for Electrophysiological Recordings from Spinal Sensory and Motor Neurons

Published on: April 18, 2017

12.1K

相关实验视频

Last Updated: Mar 4, 2026

Studying the Neural Basis of Adaptive Locomotor Behavior in Insects
10:19

Studying the Neural Basis of Adaptive Locomotor Behavior in Insects

Published on: April 13, 2011

13.3K
Kinematics and Ground Reaction Force Determination: A Demonstration Quantifying Locomotor Abilities of Young Adult, Middle-aged, and Geriatric Rats
10:28

Kinematics and Ground Reaction Force Determination: A Demonstration Quantifying Locomotor Abilities of Young Adult, Middle-aged, and Geriatric Rats

Published on: February 22, 2011

20.2K
Zebrafish In Situ Spinal Cord Preparation for Electrophysiological Recordings from Spinal Sensory and Motor Neurons
08:24

Zebrafish In Situ Spinal Cord Preparation for Electrophysiological Recordings from Spinal Sensory and Motor Neurons

Published on: April 18, 2017

12.1K