简短的药剂师主导的干预使用结构化问卷来改善对抗精神病药物的患者对药物坚持的态度:一站式前后研究
Masaki Maehara1,2, Masayasu Sugiyama3, Daisuke Kobayashi4
1Sugiyama Pharmacy Co., Ltd., 525-2 Mitsusawa, Ogoori, 838-0106, Fukuoka, Japan. mmaeharaph@yahoo.co.jp.
Annals of general psychiatry
|March 2, 2026
概括
短暂的药剂师干预显著改善了精神病患者服用抗精神病药物的药物坚持和态度. 这凸显了药剂师在支持患者坚持治疗方面发挥的关键作用.
科学领域:
- 药理学 药理学是指药理学的学科.
- 精神病学是一个精神病学.
- 医疗保健服务研究 医疗服务研究
背景情况:
- 药物坚持是精神疾病的一个主要挑战,影响临床结果.
- 药剂师的干预措施有望改善坚持,但对抗精神病药物使用者的证据有限.
- 这项研究解决了对接受抗精神病治疗的门诊患者有效的坚持策略的需求.
研究的目的:
- 评估短暂的药剂师主导干预的有效性.
- 在接受抗精神病治疗的门诊患者中增强药物坚持.
- 评估药物治疗态度的变化,并确定坚持药物治疗的障碍.
主要方法:
- 在日本社区药房进行的探索性,前性,单臂研究.
- 50名服用抗精神病药物的门诊患者参与了这项研究.
- 干预侧重于识别和解决坚持障碍;结果包括DAI-10分数和未使用药物率.
主要成果:
- 在参与者中,药物态度库存-10 (DAI-10) 评分显著改善 (平均增加2.05分,p=0.00619).
- 报告不遵守的参与者比例显著下降,从42%降至24% (p=0.0159).
- 该干预措施对药物态度和坚持行为产生了积极的影响.
结论:
- 一个简短的药剂师主导的干预有效地改善了服用抗精神病药物的患者的药物态度和药物坚持.
- 积极的药剂师参与对于支持这一群体的药物坚持至关重要.
- 研究结果支持将药剂师领导的坚持计划纳入常规精神病治疗.
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