丹麦监狱中C型肝炎的流行率和相关因素,2022-2024年:多中心跨部门研究
Jonas Demant1, Jacob Søholm2, Jeffrey V Lazarus3,4
1Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark.
Journal of viral hepatitis
|March 3, 2026
概括
在丹麦监狱的查中,C型肝炎病毒 (HCV) 发现4.2%的抗体和2.0%的RNA流行率. 针对性干预对于在脆弱的监禁人口中消除HCV至关重要.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 监狱是C型肝炎病毒 (HCV) 消除工作的关键场所.
- 关于丹麦惩戒设施内HCV患病率和风险因素的数据有限.
研究的目的:
- 确定丹麦东部监禁人员中HCV感染的流行率.
- 为了确定与该人群中HCV暴露相关的风险因素.
- 为监狱中消除HCV提供有针对性的干预信息.
主要方法:
- 从2022年10月到2024年8月,在16个丹麦东部监狱进行了一项横截面研究.
- 651名被监禁的人被录取,通过干血斑进行HCV抗体和RNA测试.
- 对所有参与者进行了生物行为风险调查.
主要成果:
- HCV抗体的患病率为4.2% (26/651) 和HCVRNA的患病率为2.0% (13/651).
- 暴露于HCV与注射药物使用史 (aOR 209.11),女性性别 (aOR 0.18) 和来自低患病率国家的外国出生 (aOR 6.22) 有显著关联.
- 在有注射药物使用史的人群中,患病率最高 (56.4%),女性 (11.3%) 和外国出生的个人 (6.7%).
结论:
- 现场层面存在显著的差异和护理差距,不成比例地影响到边缘化群体.
- 建议在监狱入狱时进行有针对性的HCV查.
- 为了实现国家HCV消除目标,设施特定和量身定制的干预措施至关重要.
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