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Updated: Jun 18, 2026

Optimization of Synthetic Proteins: Identification of Interpositional Dependencies Indicating Structurally and/or Functionally Linked Residues
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GlueFinder:一个数据驱动的框架,用于合理发现分子

Jeffrey Skolnick1, Bharath Srinivasan2,3,4,5, Hongyi Zhou1

  • 1Center for the Study of Systems Biology, Georgia Institute of Technology, 950 Atlantic Dr NW, Atlanta, Georgia 30332, United States.

Journal of chemical information and modeling
|March 3, 2026
PubMed
概括

我们开发了GlueFinder,这是一个用于发现向蛋白质降解的分子合物的计算平台. 这种无偏见的方法扩大了可以被招募的E3链酶的范围,使新的治疗策略成为可能.

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