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PRECIsE研究:对形状感应机器人辅助支气管镜的前性多中心研究,随访两年

David E Ost¹, Erik E Folch², Janani S Reisenauer³

¹Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.

Annals of the American Thoracic Society

|March 3, 2026

概括

形状感应机器人辅助支气管镜 (ssRAB) 显示出诊断小肺结节的前景,对恶性瘤达到81.3%的灵敏度. 这项多中心研究证实了其在外围肺活检早期使用的安全性和有效性.

科学领域:

肺部病理学肺部病理学
医疗机器人医疗机器人
诊断成像诊断成像诊断成像

背景情况:

指导方针建议对肺结节>8mm进行活检.
形状感应机器人辅助支气管镜 (ssRAB) 正在出现用于小结节活检.
对于早期ssRAB代,有限的多中心数据存在.

研究的目的:

评估初始ssRAB系统的安全性和性能.
在多中心环境中与新用户一起评估ssRAB.
确定外围肺结节中恶性瘤的诊断产量和敏感性.

主要方法:

未来的,多中心的观察性研究.
在没有形光束CT指导的情况下使用ssRAB,用于10-30mm的结节.
2年的随访,敏感度和诊断产量作为主要终点.
安全性被评估为次要终点.

主要成果:

在6个中心进行了305次手术;中位结节大小为17mm.
对恶性瘤的敏感度在2年内为81.3%.
诊断收益率为74.1% (ATS/ACCP) 和77.5% (中间标准).
低并发症率:肺胸病发病率为1.6%,出血率为1.0%.

结论:

第一个ssRAB代显示了对外围结节活检的令人鼓舞的性能.
该系统在新生用户中显示出强大的安全性.
ssRAB是一种可行的选择,用于诊断小的,外围的肺结节.

关键词:

支气管镜检查 (bronchoscopy) 是一种支气管镜检查.诊断产出率是指诊断产出率是指诊断产出率.肺癌是一种肺癌.周围肺部结节周围肺部结节对恶性瘤的敏感性.

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