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Updated: Jun 14, 2026

In Vitro Analysis of E3 Ubiquitin Ligase Function
06:06

In Vitro Analysis of E3 Ubiquitin Ligase Function

Published on: May 14, 2021

在Uba7 Ubiquitin-Fold域中的动态热点直接UbcH8识别

Çağdaş Dağ1,2,3,4, Mahil Lambert1,4, Alp E Kazar1

  • 1Nanofabrication and Nanocharacterization Center for Scientific and Technological Advanced Research (n2STAR), Koç University, İstanbul 34450, Turkiye.

Biochemistry
|March 3, 2026
PubMed
概括

这项研究揭示了Uba7泛基因折叠域 (UFD) 如何与UbcH8酶结构互动,澄清了干扰素刺激的15 (ISG15) 基因结合用于天生的免疫力的关键步骤.

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