临床问题解决:一名68岁的妇女患有急性非实用性图形障碍,建筑性非实用性障碍和手指不可知症
Alexis Giff1,2, Agostinho Pinheiro1,2,3, Tamara Kaplan1,2
1Department of Neurology, Harvard Medical School, Boston, MA, USA.
The Neurohospitalist
|March 3, 2026
概括
本案例研究强调了主要中枢神经系统 (CNS) 淋巴瘤如何导致写作和实践困难. 大脑中的多焦点病变会破坏视觉空间运动网络,导致这些特定的神经系统缺陷.
科学领域:
- 神经学 神经学
- 神经瘤学神经瘤学
- 认知神经科学 认知神经科学
背景情况:
- 写作困难可能源于各种神经疾病.
- 了解涉及写作和实践的特定神经网络对于诊断至关重要.
研究的目的:
- 提出一个孤立的写作和实践障碍的案例.
- 调查潜在的神经病理和受影响的大脑区域.
主要方法:
- 一个68岁的妇女的案例报告,她有逐渐增长的写作困难.
- 神经学检查,包括语言,实践和空间能力的评估.
- 磁共振成像 (MRI) 和随后的大脑活检.
主要成果:
- 患者表现出难以形成数字和字母的困难,结构性无力症和手指无知症.
- 核磁共振扫描显示了体和左下额叶的多焦点增强性病变.
- 大脑活检证实了初级中枢神经系统淋巴瘤.
结论:
- 主要中枢神经系统淋巴瘤可以表现为书面和实践中的孤立缺陷.
- 涉及到影响视觉空间运动整合网络的多焦点病变.
- 这一案例强调了在非典型的神经表现中考虑中枢神经系统淋巴瘤的重要性.
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