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在B型肝炎疫苗接种后的新生儿中发生急性全身外血瘤病:一个病例报告
Tung Viet Cao1,2, Thuy Minh Ha3, Anh Thi Van Nguyen1
1Vietnam University of Traditional Medicine, Hanoi, Vietnam.
Sage open pediatrics
|March 3, 2026
概括
新生儿的急性泛性脱血性 pustulosis (AGEP) 是罕见的,但可以是疫苗诱导的. 这一案例突出了一个新生儿在接种乙型肝炎疫苗后发展出AGEP,并通过局部治疗得到解决.
科学领域:
- 新生儿皮肤病学 新生儿皮肤病学
- 疫苗不良反应 疫苗不良反应
- 皮肤免疫学 皮肤免疫学
背景情况:
- 急性泛化脱血性 pustulosis (AGEP) 是一种罕见的,严重的皮肤不良反应,通常是药物诱导的.
- 与疫苗相关的AGEP在新生儿中不常见.
研究的目的:
- 在接种乙型肝炎疫苗后报告新生儿AGEP病例.
- 讨论临床表现,诊断考虑和婴儿疫苗相关AGEP的管理.
主要方法:
- 一个男性新生儿的临床病例报告.
- 观察临床过程,形态和对治疗的反应.
- 补丁测试与涉及的疫苗很多.
主要成果:
- 新生儿在B型肝炎疫苗接种后6小时就产生了AGEP.
- 喷发的特点是红血斑上的,在48小时内迅速消失.
- 阳性贴片试验证实了对疫苗的IV型过敏反应.
结论:
- 疫苗相关的AGEP可能发生在新生儿身上,呈现为罕见的不良反应.
- 临床表现和快速解决方案可以表明AGEP即使没有广泛的调查.
- 局部皮质类固醇在治疗新生儿AGEP方面可能是有效的.
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