硫酸用于治疗两岁以下儿童的急性支气管炎
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Updated: May 6, 2026

13:28
Methodology for Sputum Induction and Laboratory Processing
Published on: December 17, 2017
29.5K
Sudha Chandelia1, Dinesh Kumar2, Deepika Tandon3
1Department of Pediatrics, Atal Bihari Vajpayee Institute of Medical Sciences (formerly PGIMER) and Dr Ram Manohar Lohia Hospital, New Delhi, India.
The Cochrane database of systematic reviews
|March 3, 2026
概括
硫酸对两岁以下儿童急性支气管炎的有效性尚不清楚. 需要更多的研究来确定益处和危害.
科学领域:
- 儿科 儿科 儿科
- 呼吸系统医学 呼吸系统医学
- 药理学 药理学是指药理学的学科.
背景情况:
- 急性支气管炎是婴儿常见的呼吸道感染.
- 硫酸在治疗急性支气管炎中的作用仍然不确定.
- 目前关于硫酸在幼儿中的疗效的数据有限.
研究的目的:
- 评估硫酸在患有急性支气管炎的两岁以下儿童的作用.
- 从随机对照试验和非随机研究中综合证据.
- 评估关键结果,包括恢复时间,死亡率和不良事件.
主要方法:
- 在多个数据库 (CENTRAL,MEDLINE,Embase等) 进行了搜索. 在2024年11月之前.
- 包括随机对照试验 (RCT) 和非随机研究.
- 使用Cochrane的RoB 1工具评估偏差风险和使用GRADE的证据确定性.
主要成果:
- 包括7项涉及816名儿童的试验.
- 对硫酸对康复,死亡率和不良事件的影响的证据确定性非常低.
- 与安慰剂相比,硫酸可能会增加再入院率 (低确定性证据).
结论:
- 目前的证据不足以确定硫酸对幼儿急性支气管炎的益处或危害.
- 需要高质量的RCT来研究硫酸的疗效.
- 未来的研究应该关注康复时间,不良事件和住院时间.
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