在门诊膝关节关节镜术中用于脊柱麻醉的罗普洛卡因与普罗洛卡因:使用基于活动的成本计算的前性经济评估
C Franceschi1, F Tasso, V Simili
1IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy. carlotta.franceschi@humanitas.it.
European review for medical and pharmacological sciences
|March 3, 2026
概括
在膝关节关节镜术中使用洛卡因的脊柱麻醉,与 prilocaine 相比,显著降低了成本和恢复时间. 这项研究强调了罗普罗卡因作为骨科日间医院手术中更具成本效益的麻醉选择.
科学领域:
- 麻醉学 麻醉学
- 整形外科手术 整形外科手术
- 卫生经济学 卫生经济学
背景情况:
- 选择短效局部麻醉剂用于脊柱麻醉在骨科日间医院手术,如膝关节透镜,可以影响患者的康复和医疗保健费用.
- 优化麻醉选择对于提高门诊外科手术设置的效率和成本效益至关重要.
研究的目的:
- 为了比较罗普罗卡因与普罗洛卡因在选择性膝关节关节镜术期间的脊柱麻醉的成本效益和术后结果.
- 评估不同局部麻醉剂对手术成本,康复时间和骨科日间医院环境中的不良事件的影响.
主要方法:
- 一项前性,双臂队列研究,涉及70名接受膝关节关节镜术进行脑膜切除术的成年患者.
- 患者接受脊髓洛卡因 (40毫克,1%) 或洛卡因 (40毫克,2%) 的治疗.
- 基于活动的成本计算方法用于分析成本,包括手术室时间,康复室时间,护理和医生护理,药物使用和计划外住院. 术后指标和不良事件是次要结果.
主要成果:
- 与普罗洛卡因 (€938.09) 相比,每位患者的平均手术成本与洛卡因 (€604.76) 相比显著降低.
- 康复室时间和麻醉师护理时间在罗普罗卡因组大幅减少 (p < 0.001).
- 五名接受普里洛卡因治疗的患者发生了尿,一名患者需要住院一夜,而在洛卡因组中没有这种事件.
结论:
- 脊柱洛卡因与膝关节关节镜检查中的prilocaine相比,与显著缩短的术后护理时间和较低的医院相关费用有关.
- хлоропрокаин表现出药物经济优势,表明其作为一种具有成本效益的麻醉选择的潜力.
- 建议进一步进行高质量,多中心的随机对照试验,以验证这些发现并确认罗普罗卡因的成本效益.
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