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Updated: Jun 9, 2026

Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers
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Published on: September 19, 2017

通过特定站点的脊柱修改来操纵折叠蛋白质的未折叠状态

Gabrielle E Page1, Yuhan Lin1, W Seth Horne1

  • 1Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.

Biochemistry
|March 3, 2026
PubMed
概括

研究人员修改了蛋白质脊柱以调整它们的展开状态,发现折叠稳定性的可预测变化. 这种方法提供了研究蛋白质折叠和设计蛋白质模拟的新方法.

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Residue-Specific Exchange of Proline by Proline Analogs in Fluorescent Proteins: How "Molecular Surgery" of the Backbone Affects Folding and Stability10:31

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