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在支持CSFV复制和抑制RLR信号传输方面,ER-Golgi货物受体LMAN1的双重作用

Kailiang Han1, Zhaoyu Chang1, Ning Li1

  • 1College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, People's Republic of China.

Journal of virology
|March 3, 2026
PubMed
概括

主体蛋白质LMAN1通过结合病毒聚合酶和抑制抗病毒反应促进古典猪瘟病毒 (CSFV) 复制. 失去LMAN1会阻碍CSFV的扩散,并增强先天免疫力,从而确定LMAN1是病毒与宿主相互作用的关键目标.

关键词:
在NS5B中,它是NS5B.在RLR路径上.RNA合成的RNA合成经典猪瘟病毒 (CSFV) 是一种猪瘟病毒.莱克,曼诺结合剂1 (LMAN1) 的作用.

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