母亲对口腔微生物群发育的影响和对幼儿健康的影响:系统性审查
Audrey Wang1, Lien Quynh Dao2, Francisco Ramos-Gomez3
1Department of Psychobiology, University of California Los Angeles, Los Angeles, California, USA.
Infection and immunity
|March 3, 2026
概括
母亲是婴儿口腔微生物组建立的关键来源. 母婴口腔微生物组在第一年变得更加相似,到5岁时稳定.
科学领域:
- 微生物学 微生物学
- 发展生物学 发展生物学
- 人类健康 人类健康 人类健康
背景情况:
- 关于影响早期口腔微生物组发育的母婴相互作用的研究有限.
- 了解这些联系对于潜在的临床应用至关重要.
研究的目的:
- 对从出生到五岁口腔微生物组发育的纵向研究进行系统审查.
- 分析母亲和婴儿口腔微生物组之间的关系.
主要方法:
- 在PubMed,Cochrane图书馆和Embase进行系统搜索 (2025年6月).
- 纳入标准:纵向设计,健康的母婴二合体,唾液样本,相关年龄段.
- 排除标准:评论文章,非英语,数据重叠.
主要成果:
- 母亲是新生儿初始口腔微生物群殖民的重要来源.
- 婴儿口腔微生物组最初是多样化和非专业化的,有来自母亲的菌株.
- 微生物组的多样性增加,在第一年内类似于母亲的微生物组,在3-5年稳定下来.
结论:
- 母婴微生物连接在幼儿时期显著影响口腔微生物组的发展.
- 未来的研究需要更大的纵向研究,使用先进的工具来探索诸如分娩方式和父母习惯等因素.
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