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Francesco Giganti^1,2, Clare Allen¹, Louise Dickinson¹

¹Department of Radiology, University College London Hospital NHS Foundation Trust, 43-45 Foley St, Charles Bell House, 3rd Floor, London, W1W 7TS, United Kingdom.

|March 3, 2026

概括

前列腺癌的积极监测使用连续的MRI扫描来监测疾病的进展. PRECISE评分系统标准化了MRI解释,指导治疗决策并优化了患者管理.

科学领域:

放射学放射学是一门学科.
在瘤学瘤学.
泌尿器科泌尿器科泌尿器科泌尿器科

背景情况:

积极监测 (AS) 是低至中等风险前列腺癌的管理选择,推迟立即治疗.
连续磁共振成像 (MRI) 有助于患者选择和非侵入性监测AS期间的瘤进展.
标准化MRI解释对于一致的患者管理至关重要.

研究的目的:

通过使用PRECISE评分系统标准化前列腺癌患者的MRI解释.
讨论测量瘤大小随时间变化的最佳方法.
确定临床上有意义的进展标准,并指导治疗的开始.

主要方法:

在第三级推中心使用了20多年的入门和AS期间的常规MRI.
应用了前列腺癌辐射估计变化序列评估 (PRECISE) 评分系统 (1-5级).
讨论了各种瘤大小测量技术 (一/两轴,圆方程式,平面测量),偏好单个观察者进行例行体积测量.

主要成果:

PRECISE系统将放射性变化分类为回归 (1-2),稳定性 (3) 或进展 (4-5).
基于风险类别优化MRI间隔的既定方法.
定义的大小变化和MRI外观表明临床上显著的进展.

结论:

通过PRECISE评分的标准化MRI解释可以提高AS患者的管理.
通过单个观察者进行例行瘤体积测量,有利于跟踪进展.
优化的MRI协议和明确的进展标准促进前列腺癌AS的及时治疗决策.

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