在膝关节骨关节炎中,单次静脉跨直接电流刺激对运动诱导的低痛症没有影响:随机交叉试验
David Toomey1, Gwyn Lewis1, Usman Rashid1
1Auckland University of Technology, Auckland, New Zealand.
概括
跨直流刺激 (tDCS) 在膝关节骨关节炎 (OA) 患者中没有增强运动诱导的疼痛缓解. 单次阳道tDCS治疗没有显著改善运动后的疼痛门或膝盖疼痛.
科学领域:
- 神经科学是一个神经科学.
- 疼痛管理 疼痛管理
- 康复科学 康复科学 康复科学
背景情况:
- 运动诱导的低痛症 (EIH) 是一种短期缓解疼痛的现象.
- 患有膝关节骨关节炎 (OA) 的人通常会表现出的EIH反应.
- 越直流刺激 (tDCS) 被探索为一种可能增强EIH的方法.
研究的目的:
- 调查单次2mA阳极tDCS在运动皮层上的治疗是否可以增加膝关节OA患者的EIH.
- 为了评估tDCS对平度四头肌运动期间和之后疼痛感知的影响.
主要方法:
- 一个双盲,随机,交叉试验,涉及27名膝关节OA的参与者.
- 参与者进行了两次会议:积极的阳极tDCS + 练习和假的tDCS + 练习.
- 疼痛结果包括压力疼痛值 (PPT),休息膝痛和唤起膝痛在干预前和后被测量.
主要成果:
- 积极的和假的tDCS会话都成功诱导了EIH,通过增加膝盖PPT (p ≤ 0.001) 表示.
- 对于膝盖PPT,前臂PPT,静止膝关节疼痛或唤起膝关节疼痛,在活跃和假装的tDCS条件之间没有发现显著差异.
- 失明是成功的,在研究期间没有报告任何不良事件.
结论:
- 单次阳极tDCS治疗不会增加膝关节OA患者的立即运动诱导的低疼痛反应.
- 目前的研究结果表明,tDCS可能不是一种有效的策略来增强运动诱导的疼痛缓解在这个人群.
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