对恶性胃肠道阻塞的医院利用率和治疗方式的多州队列研究
Rachael C Acker1,2,3, Jasmine Hwang1,2,3, Shane Williams1,3
1Department of Surgery, University of Pennsylvania Health System, Philadelphia, PA.
患有更多癌症住院的患者因恶性阻塞而接受的手术较少. 这一趋势影响了治疗决策和胃肠道癌症患者咨询.
科学领域:
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
背景情况:
- 恶性阻塞严重影响患者的发病率,死亡率和生活质量.
- 有限的基于人口的数据存在于管理恶性阻塞的实践模式.
- 了解影响治疗的因素对于改善患者治疗结果至关重要.
研究的目的:
- 调查与癌症相关的先前住院病人的关系,以及因恶性胃肠道阻塞而接受手术治疗的可能性.
- 分析以前住院次数如何影响恶性阻塞的手术干预.
- 为患有恶性阻塞的患者提供治疗趋势的数据.
主要方法:
- 使用医疗保健成本和利用项目国家住院患者数据库 (2016-2020) 的回顾性队列研究.
- 包括患有由结直肠,妇科 (GYN) 和肝胰腺胆道 (HPB) 癌症引起的恶性胃肠道阻塞的患者.
- 主要暴露:在阻塞性住院之前的一年中,癌症相关住院的数量;分析了手术治疗,住院招生,住院时间和住院死亡率.
主要成果:
- 总共分析了8665名患者;24.1%接受了手术治疗.
- 以前住院的患者不太可能接受手术 (-7.8%的差异,p<0.001).
- 手术治疗与更长的住院时间,更低的住院入院率和减少住院患者死亡率相关.
结论:
- 先前癌症住院的增加与恶性阻塞的手术治疗率下降有关.
- 这些发现提供了对恶性阻塞的当前治疗趋势的见解.
- 这些数据可以帮助患者就疾病的自然进展和治疗选择进行咨询.
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