概括
快速眼动睡眠行为障碍 (RBD) 的研究显著增加,转向早期检测和神经退行性疾病预测. 全球合作是了解这种快速眼动睡眠障碍及其与帕金森病的联系的关键.
科学领域:
- 神经学 神经学
- 睡眠医学 睡眠医学
- 图书统计学 图书统计学
背景情况:
- 快速眼动睡眠行为障碍 (RBD) 是一种在REM睡眠期间肌肉丧的表征.
- 脊髓脊髓损伤与神经退行性疾病密切相关,特别是像帕金森病这样的α-synucleinopathies.
- 本研究提供了2010年至2025年全球RBD研究的文献分析.
研究的目的:
- 进行全球研究趋势的图书统计概述 快速眼动睡眠行为障碍 (RBD).
- 分析出版成果,地理分布,机构合作和RBD的关键研究主题.
- 确定研究重点从临床表征到翻译方法的演变.
主要方法:
- 分析了来自Web of Science和Scopus数据库的4204个出版物.
- 使用了包括CiteSpace,VOSviewer,Python和R (bibliometrix) 在内的图书识别工具.
- 研究了出版趋势,地理和机构贡献,作者影响,期刊影响和关键词演变.
主要成果:
- 稳步增加RBD出版物,在2015年后加速增长.
- 美国,中国和加拿大在贡献方面领先,其中包括多伦多大学,梅奥诊所和北京大学在内的著名机构.
- 研究重点转向生物标志物识别,早期干预,α-synuclein病理学,前期帕金森病和黑激素治疗.
结论:
- 脊髓神经疾病的研究越来越多地转化,专注于早期检测和神经退行性风险预测.
- 全球合作正在提高对RBD机制及其预测价值的理解.
- 该领域对RBD的机制性见解和治疗策略越来越感兴趣.
相关概念视频
Sleep-Wake Cycles
Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
Understanding Sleep
Sleep, an essential biological state, involves significant reductions in physical activity, sensory awareness, and interaction with the environment. This complex physiological process is primarily regulated by specific brain regions, notably the hypothalamus and pons, which govern the sleep-wake cycle or circadian rhythm.
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...
Sleepwalking and Sleep Talking
Somnambulism, commonly known as sleepwalking, involves individuals engaging in activities ranging from simple walking to more complex behaviors such as driving. Sleepwalking typically occurs during the slow-wave sleep stages 3 and 4 early in the night when the person is not dreaming, contradicting the myth that sleepwalkers are acting out their dreams.
Factors that increase the likelihood of sleepwalking include sleep deprivation and alcohol consumption. Contrary to common beliefs, it is safe...
Factors that increase the likelihood of sleepwalking include sleep deprivation and alcohol consumption. Contrary to common beliefs, it is safe...
REM Sleep Behavior Disorder
REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
RBD is significantly associated with...
Narcolepsy
Narcolepsy is a chronic sleep disorder characterized by pervasive, uncontrolled sleepiness and other sleep disturbances. One of its hallmark symptoms is an abrupt transition to REM sleep upon falling asleep, which causes symptoms typically associated with this phase to occur unexpectedly during wakefulness. These include the following symptoms, which typically last from a minute or two to half an hour.
Nightmares and Night Terrors
Nightmares and night terrors represent two distinct types of sleep disturbances that differ in timing, characteristics, and the sleeper's recall of the event. Nightmares are vivid, disturbing dreams that usually awaken the sleeper from REM sleep, a stage of sleep where brain activity is high, and dreams are most frequent. Upon awakening, individuals often have detailed recollections of their nightmares, which can include themes of threats to survival, security, or self-esteem.
Nightmares often...
Nightmares often...


