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Updated: Jul 7, 2026

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
08:32

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production

Published on: March 2, 2014

CD97-PPM1G轴通过在I型干扰素通路中去酸化IRF7来抑制抗病毒免疫力

Huasong Chang1, Wenjing Qi1, Rukun Yang1

  • 1Ruminant Diseases Research Center, College of Life Sciences, Shandong Normal University, Jinan, Shandong, China.

PLoS pathogens
|March 3, 2026
PubMed
概括

分化集群97 (CD97) 通过去酸化干扰素调节因子7 (IRF7) 来抑制I型干扰素 (IFN-I) 信号传递,从而促进病毒复制. 阻止CD97增强了抗病毒防御.

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A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF311:44

A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3

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