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Updated: Jul 6, 2026

An In Ovo Model for Testing Insulin-mimetic Compounds
06:09

An In Ovo Model for Testing Insulin-mimetic Compounds

Published on: April 23, 2018

基于森林的随机QSAR和分子动力学的洞察力,对类固醇怀孕作为11β-hydroxysteroid脱酶1型调节剂的洞察力,用于2型糖尿病

Oludare M Ogunyemi1, Gideon A Gyebi2, Oladimeji S Macaulay1

  • 1Structural and Computational Biology Group, Nutritional and Industrial Biochemistry Research Unit, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan 200005, Nigeria.

Computational biology and chemistry
|March 3, 2026
PubMed
概括

类固醇怀孕在2型糖尿病中显示出11β-HSD1抑制剂的潜力. 计算方法确定了增强结合亲和力和潜在治疗发展的关键结构特征.

关键词:
11β-HSD1 抑制剂的使用和动力学模拟.发现抗糖尿病药物发现.机器学习是机器学习.分子对接是分子对接.类固醇妊娠 类固醇怀孕

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