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Updated: Aug 7, 2026

Experimental Protocol for Detecting Mitochondrial Function in Hepatocytes Exposed to Organochlorine Pesticides
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血有机酸暴露相关的microRNA表达特征及其在中国健康成年人中的功能分析

Xulin Zhang1, Zirui Zhang1, Yuxin Xu1

  • 1Department of Occupational and Environmental Health, Key Laboratory of Environment and Health, Ministry of Education and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

Environmental research
|March 3, 2026
PubMed
概括

这项研究将有机酸 (OPEs) 暴露与成年人血微RNA (miRNA) 形状的改变联系起来. 结果表明潜在的神经毒性作用,并突出了低水平OPE污染的公共卫生问题.

关键词:
有机酸盐 Ester 是一种有机酸盐.白细胞转录组是白细胞的转录组.这是一个微型RNA.神经毒性的作用.路径丰富方式

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MicroRNAs01:22

MicroRNAs

MicroRNA (miRNA) are short, regulatory RNA transcribed from introns—non-coding regions of a gene—or intergenic regions—stretches of DNA present between genes. Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA ends...
MicroRNAs01:22

MicroRNAs

MicroRNA (miRNA) are short, regulatory RNA transcribed from introns (non-coding regions of a gene) or intergenic regions (stretches of DNA present between genes). Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself, forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA...