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激进前列腺切除术后的丸激素缺乏症的病因
Muhammed A M Hammad1, Dhiresh Bandaru1, Vada Furlan2
1Department of Urology, University of California Irvine, Irvine, CA.
Urologic oncology
|March 3, 2026
概括
激进前列腺切除术 (RP) 后,缺乏症 (TD) 影响高达30%的男性,通常在一年内消失. 了解RP后TD的原因对于管理患者健康至关重要.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 内分泌学 在内分泌学.
- 男人的健康 男人的健康
背景情况:
- 缺乏症 (TD) 是根源性前列腺切除术 (RP) 后的潜在并发症.
- 在这种情况下,关于替代疗法 (TRT) 的患病率,机制和安全性的指导是有限的.
研究的目的:
- 综合当前关于激进前列腺切除术后丸激素缺乏原因的证据.
- 为了提供一个全面的概述后RPTD的病因学.
主要方法:
- 根据PRISMA-ScR指南进行了系统范围审查.
- 确定并选了研究RP后TD病因学的英语人体研究.
- 从186篇选的文章中,有14项研究符合纳入标准.
主要成果:
- 在急性前列腺切除术 (RP) 四周内,在20%~30%的男性中观察到丸激素缺乏 (TD).
- 在手术后90天,TD在37.5%的患者中持续存在.
- 潜在的促成因素包括外科手术期间的静脉,缺血和神经内分泌干扰,尽管证据是间接的.
结论:
- 大约三分之一的男性在RP后经历临时或持续的TD,与静脉,缺血和内分泌因素有关.
- 大多数TD病例在一年内消失.
- 建议进行进一步的研究,包括常规的雄激素监测和前性试验,以优化RP后的TRT策略.
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