烟斗和雪茄使用,肺功能下降和临床结果:对NHLBI聚合队列研究的分析
William M Gardner1, Pallavi P Balte1, Christina M Eckhardt1
1Department of Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, New York, USA.
Thorax
|March 3, 2026
概括
烟斗和雪茄的使用显著加快肺功能下降和增加死亡率,即使在从未吸过香烟的人. 这些发现凸显了针对非烟草烟草产品的有针对性的预防和戒烟计划的迫切需要.
科学领域:
- 心肺健康 心肺健康
- 烟草控制研究研究 烟草控制研究
- 公共卫生 公共卫生
背景情况:
- 吸烟烟草是心肺疾病的主要危险因素.
- 尽管烟斗和雪茄的使用率很高,但与烟斗和雪茄相关的健康风险尚未完全理解.
研究的目的:
- 调查烟斗和雪茄使用与心肺健康结果之间的关联.
- 量化专用烟斗和雪茄使用对肺功能和死亡率的影响.
主要方法:
- 来自五个队列 (1971-2018) 的汇总数据的分析,包括螺旋计测量 (FEV1,FVC,FEV1/FVC).
- 使用经过验证的算法评估所有原因死亡率,冠心病和COPD相关事件.
- 统计建模 (线性混合模型,细灰模型) 经过调整以考虑混因素.
主要成果:
- 与非烟草使用者相比,单独使用烟斗/雪茄与FEV1,FVC和FEV1/FVC比率的加速下降相关.
- 独家使用者表现出增加的全因死亡率,COPD住院/死亡率,以及维护比率受损的螺旋计.
- 关联仍然很重要,即使对于没有先前吸烟史的独家使用者来说.
结论:
- 烟斗和雪茄的消费与更快的肺功能下降和心肺风险增加有关.
- 调查结果强调了对非烟草烟草制品的预防和戒烟战略的必要性.
- 公共卫生倡议应全面解决烟斗和雪茄使用的风险.
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