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Updated: May 3, 2026

Profiling Thiol Redox Proteome Using Isotope Tagging Mass Spectrometry
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Profiling Thiol Redox Proteome Using Isotope Tagging Mass Spectrometry

Published on: March 24, 2012

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通过活细胞标签实现的单细胞醇分析揭示了铁灭中的代谢异质性

Daiyu Miao1, Qiuning Li1, Yi Zhang1

  • 1Beijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing, China.

Nature communications
|March 3, 2026
PubMed
概括

这项研究引入了一种新方法,用于使用活细胞标记和质细胞计量在单细胞中分析醇. 这种技术准确地测量了代谢变化,并揭示了RSL3如何在铁灭过程中影响谷氨合成.

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Resin-Assisted Capture Coupled with Isobaric Tandem Mass Tag Labeling for Multiplexed Quantification of Protein Thiol Oxidation

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Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics04:01

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics

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相关概念视频

Overview Of Cell Separation And Isolation01:20

Overview Of Cell Separation And Isolation

Cell separation was first achieved in 1964 by S. H. Seal, who separated large tumor cells from the smaller blood cells using filtration. Two years later, Pohl and Hawk performed experiments on how cells respond differently to a nonuniform electric field based on the cell type. Such observations were the inception of cell separation methods, which allow isolating a single cell type from a heterogeneous sample.
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