组织性宫癌查计划对发病率和死亡率的影响:系统性审查和元分析
Ivana Nikcevic Kovacevic1, Aleksa Jovanovic2, Jovana Ristic2
1Institute of Public Health of Montenegro, Podgorica, Montenegro.
Journal of prevention (2022)
|March 3, 2026
概括
有组织的宫癌查计划显著降低了患宫癌或死于宫癌的风险. 定期参与是关键;与没有查相比,不规则的查几乎没有好处.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 宫癌仍然是一个重大的全球健康问题.
- 通过查进行早期检测对于降低发病率和死亡率至关重要.
- 组织查计划的影响需要持续评估.
研究的目的:
- 系统地审查和元分析有组织查计划对宫癌发病率和死亡率的影响.
- 评估定期与不定期参与查计划的有效性.
主要方法:
- 按照PRISMA 2020指南进行系统的文献审查,搜索PubMed,Scopus和科学网络.
- 使用纽卡斯尔-太华尺度进行质量评估.
- 随机效应的元分析,使用Hartung-Knapp调整和逆方差方法来计算聚合效应大小.
主要成果:
- 定期参加有组织的宫癌查,可显著降低患宫癌 (OR=0.40) 和死于宫癌 (OR=0.31) 的可能性.
- 在发病率和死亡率的研究中发现了显著的异质性.
- 埃格尔和贝格的测试表明没有出版偏差 (p<0.05).
结论:
- 有组织的宫癌查计划可以有效地减少癌症发病率和死亡率,特别是在定期参与的情况下.
- 不规则地参加查计划带来最小的保护性益处,风险与非参与者相比较.
- 强调定期参加查对于最大限度地提高这些计划对公共卫生的影响至关重要.
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