相关实验视频

Updated: Jun 17, 2026

Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing
11:02

Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing

Published on: October 18, 2013

儿科固体瘤的综合性基因组分析揭示了临床相关的变体和染色体臂形形状的签名

Bingxiao Yan1,2,3,4, Jinhu Wang1,3,4,5,6, Jieni Xiong1,4

  • 1Department of Surgical Oncology, Children's Hospital Zhejiang University School of Medicine, National Clinical Research Center for Children and Adolescents' Health and Diseases, Hangzhou, Zhejiang, China.

Cancer medicine
|March 3, 2026
PubMed
概括

这项研究揭示了中国儿科固体瘤的关键基因组变化,确定了治疗标和与成人癌症相比明显的染色体不稳定模式,以改善儿童癌症治疗.

关键词:
染色体手臂发生了形化.临床相关的变种.生殖线倾向变体的生殖线倾向变体儿科的固体瘤

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Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
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Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
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