过渡性缺血性发作的发病率和发生率:系统性审查和元分析
Ni Zhang1, Juan Guo2, Wenwen Liu3
1School of Nursing, Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, 271016, China.
BMC neurology
|March 3, 2026
概括
过渡性缺血性发作 (TIA) 是一个重要的中风预测因素. 这一系统性审查显示,全球TIA患病率为1.95%,亚洲和老年人患病率更高,强调需要标准化诊断.
科学领域:
- 神经学 神经学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 过渡性缺血性攻击 (TIA) 是中风的关键预测因素.
- 经过TIA的病例具有很高的复发风险,并可能导致各种后果.
- 了解TIA流行病学对于有效的预防和干预至关重要.
研究的目的:
- 系统地审查和元分析TIA的流行病学特征和趋势.
- 为了确定TIA的高风险人群.
- 为TIA预防和干预策略提供一个证据基础.
主要方法:
- 按照PRISMA 2020指南进行系统审查和元分析.
- 从创立到2024年10月,搜索了主要的英语和中文数据库.
- 包括TIA患病率/发病率的横截面或队列研究;使用随机效应模型合成的数据.
主要成果:
- 分析了47项研究 (50个数据集);全球TIA患病率为1.95%.
- 在亚洲 (2.19%) 和65岁以上的成年人 (5.13%) 中,患病率更高.
- 年均发病率为54/100,000人/年,在美洲最高 (81/100,000);发病率随着时间的推移而下降,但随着年龄的增长而增加.
结论:
- 全球TIA流行病学显示,根据诊断标准,年龄和地区存在显著差异.
- 异质性和报告不足需要标准化,基于成像的诊断协议.
- 开发风险分层工具和特定区域的预防措施对于降低TIA负担至关重要.
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