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Updated: Jun 25, 2026

Identifying the Effects of BRCA1 Mutations on Homologous Recombination using Cells that Express Endogenous Wild-type BRCA1
08:53

Identifying the Effects of BRCA1 Mutations on Homologous Recombination using Cells that Express Endogenous Wild-type BRCA1

Published on: February 18, 2011

对于BRCA1和BRCA2致病变体携带者的非乳腺,非卵巢癌风险:一个前性队列研究

Ruotong Yang1,2, Robert J MacInnis1,3, Roger L Milne1,3,4

  • 1Center for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Carlton, VIC, Australia.

BMC medicine
|March 3, 2026
PubMed
概括

携带BRCA1和BRCA2病原性变异的携带者有明显增加的胰腺癌和前列腺癌的风险,特别是BRCA2携带者. 其他非乳腺,非卵巢癌的风险基本保持不变.

关键词:
这就是BRCA1的原因.这就是BRCA2的原因.癌症风险 癌症风险 癌症风险透性 透性的未来的研究研究前性研究.

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