心脏代谢指数和抑郁症状之间的形状关联:美国成年人的基于人口的横截面研究
Zhihong Yu1,2, Wei Li1,2, Meng Wang1,2
1Department of Critical Care Medicine, the Second Affiliated Hospital of Nanchang University, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China.
European journal of medical research
|March 3, 2026
概括
较高的心脏代谢指数 (CMI) 与身体质量指数 (BMI) 25 或以上的成年人抑郁症状增加有关. 确定了一个值效应,表明了这种关联的转折点.
科学领域:
- 心脏病学 心脏病学
- 代谢健康 代谢健康
- 精神病学是一个精神病学.
背景情况:
- 关于心脏代谢指数 (CMI) 和抑郁症状之间的联系的研究有限.
- 这项研究调查了成人中CMI和抑郁症状之间的潜在关系.
研究的目的:
- 评估心脏代谢指数 (CMI) 和抑郁症状之间的关联.
- 识别潜在的非线性关系和值效应.
主要方法:
- 从国家健康和营养检查调查 (NHANES) (2007-2018) 中对7965名成年人的横截面分析.
- 使用患者健康问卷-9 (PHQ-9) 评估的抑郁症状;得分≥10表示存在.
- 多变量逻辑回归,受限制的立方线,和零碎的逻辑回归被用来分析关联,并确定拐点.
主要成果:
- 在CMI和抑郁症状之间发现了一个J形的非线性关联.
- 在一定CMI值以下没有观察到任何关联 (LnCMI < -2).
- 在这个值以上 (LnCMI ≥-2),较高的CMI与抑郁症状 (OR 1.92) 有积极的关联. 体重指数 (BMI) 调节了这一关联 (OR 2.37).
结论:
- 较高的心脏代谢指数 (CMI) 水平与抑郁症状的患病率增加密切相关.
- 这种关联在美国成年人中尤为显著,BMI≥25kg/m2.
- 确定了一个值效应,表明一个特定的CMI水平,超出该值后,抑郁症状的风险显著增加.
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