[血管内流量的矢量映射,以评估内动脉狭窄症患者的壁切应力]
V A Sandrikov1, E F Dutikova1, A V Gavrilenko1
1Russian Research Center of Surgery named after Academician B.V. Petrovsky, 119991, Moscow, Russian Federation.
概括
动脉内关节切除术使内动脉狭窄症患者的壁切应力和血流正常化. 矢量流量映射有效评估脑血管疾病的手术结果.
科学领域:
- 心血管成像和血液动力学
- 血管外科手术的结果
- 血液流动的生物机械分析.
背景情况:
- 内动脉狭窄 (ICA) 构成脑血管事件的重大风险.
- 评估ICA狭窄的血液动力学影响和手术干预的有效性至关重要.
- 壁切应力 (WSS) 是一个由血液流动动力学影响的关键生物力学因素.
研究的目的:
- 使用矢量流量映射评估ICA壁切应力 (WSS) 的动态变化.
- 视觉化和量化血液流动模式之前和之后的动脉内关节切除术.
- 建立WSS作为评估动脉内关节切除术有效性的标准.
主要方法:
- 使用V流软件的超声波和用于矢量流分析的线性传感器.
- 在ICA中测量WSS,振荡切割指数 (OSI) 和血液流速 (Vs).
- 与WSS相关的流和使用ECST方法评估的ICA狭窄.
主要成果:
- 在ACA狭窄的动在心经收缩期间显著高于心经扩张.
- 手术前的流显示出与WSS有显著的相关性.
- 手术后的正常化WSS和OSI值表明ICA狭窄的适当纠正 (>70%).
结论:
- 血流方向上升的WSS是ICA狭窄症中流的特征.
- 术后流量向量恢复到正常值是成功手术纠正的标准.
- WSS的矢量流量映射为评估脑血管疾病手术结果提供了一种新的方法.
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