保存比率受损螺旋计的患病率:一个系统的审查和元分析
Yiting Li1,2, Peng Zhang1, Yan Wang1,2
1Department of Respiratory Diseases, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, Henan, China.
Pulmonology
|March 4, 2026
概括
保留比率受损螺旋计 (PRISm) 影响10%的人,与吸烟,并发病症和较高的死亡率有关. 了解PRISm的流行是临床管理和预防策略的关键.
科学领域:
- 肺部医学 肺部医学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 维护比率受损螺旋计 (PRISm) 是一个未被认可的条件.
- 它的流行率和临床影响需要进一步阐明.
研究的目的:
- 为了确定PRISm的全球流行情况.
- 为了确定相关的风险因素和并发症.
- 调查PRISm患者的死亡率和肺功能轨迹.
主要方法:
- 在PubMed,Embase,Web of Science和Cochrane图书馆的系统文献搜索.
- 24项队列研究的元分析,其中包括33项最初符合条件的研究.
- 评估研究质量,偏差风险和出版偏差.
主要成果:
- 普里斯姆的综合流行率为10% (95% CI:0.08,0.12).
- 吸烟是显著的风险因素;与呼吸道症状没有关联.
- PRISm与高血压,糖尿病,心血管疾病,中风相关,并增加了全因和心血管死亡率.
- 肺功能轨迹各不相同,在6-53%的病例中观察到慢性肺炎的进展.
结论:
- PRISm是普遍存在的,并与严重的健康风险相关,包括心脏代谢性并发症和增加的死亡率.
- 这些发现突显了PRISm的临床重要性,超出了它与COPD的关联.
- 为了有效的预防和管理策略,需要进一步的研究和临床关注.
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