脑卒中后不久的睡眠呼吸障碍与3个月后的脑卒中后疲劳无关
Christopher J Becker1, Lynda D Lisabeth2, William Duncker2
1Department of Neurology, University of Michigan.
概括
在中风后不久的睡眠呼吸障碍并不能预测三个月后的中风后疲劳. 这些发现表明,治疗睡眠呼吸障碍可能不会减轻中风幸存者的疲劳.
科学领域:
- 神经学 神经学
- 睡眠医学 睡眠医学
- 心血管研究研究心血管研究
背景情况:
- 脑卒中后疲劳 (PSF) 是中风后的一个普遍且经常使人衰弱的疾病.
- 聚乙烯纤维的根本原因仍然不清楚,需要进一步调查.
- 睡眠呼吸障碍 (SDB) 在中风后很常见,已知会导致疲劳.
研究的目的:
- 评估中风后不久测量的SDB和3个月后的PSF之间的关联.
- 确定SDB是否可以成为管理PSF的潜在干预目标.
主要方法:
- 一项涉及缺血性中风 (IS) 患者的多中心队列研究.
- 使用家庭睡眠呼吸暂停测试 (ApneaLink PlusTM) 测量呼吸事件指数 (REI) 的夜间SDB查.
- 在中风后3个月使用SF-36活力尺度评估PSF;多变量线性回归被用于分析.
主要成果:
- 355名IS参与者完成了基线SDB查和3个月的PSF评估.
- SDB是常见的,基线REI的中位数为17. 在调整后的模型中,在基线REI和3个月后的PSF之间没有发现显著的关联.
- 年龄和墨西哥裔美国人的种族与较低的疲劳相关,而女性性别和抑郁症治疗与较高的疲劳相关.
结论:
- 在中风后的立即时期,睡眠呼吸障碍并不能预测3个月后的中风后疲劳.
- 虽然鉴定和治疗中风后的SDB可能因为其他原因而很重要,但它不太可能影响PSF.
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