超越常态:阿斯伯吉洛症的非典型表现
Leila Zahiri1, Mohammad Javad Fallahi2, Massood Hosseinzadeh3
1Pulmonary Research Center Shiraz University of Medical Science Shiraz Iran.
Respirology case reports
|March 4, 2026
概括
这一案例突出了移植患者中由Aspergillus fumigatus引起的异常软组织感染. 通过活检和分子检测进行早期诊断对于免疫受损的个体至关重要.
科学领域:
- 医学真菌学 医学真菌学
- 传染性疾病 传染性疾病
- 移植医学 移植医学
背景情况:
- Aspergillus fumigatus通常会导致肺部疾病,特别是在免疫功能低下的患者中.
- 侵入性阿斯伯吉洛症对移植接受者构成重大威胁.
- 软组织受到Aspergillus的干扰是罕见的,但在临床上是相关的.
研究的目的:
- 报告一个罕见的Aspergillus软组织感染病例,发生在接受脏移植的人身上.
- 强调诊断的挑战和考虑在免疫力低下的患者和软组织群体的真菌感染的重要性.
主要方法:
- 一个62岁的女性移植接受者的病例报告.
- 临床表现:胸痛,胸壁质块,咳,厌食症.
- 诊断工作:实验室评估,支气管支气管洗 (BAL) 寻找Aspergillus galactomannan抗原,胸壁质量活检.
主要成果:
- 观察到炎症标志物升高.
- 在BAL检测中,Aspergillus galactomannan抗原呈阳性.
- 活检证实了软组织质的阿斯伯吉勒斯感染.
结论:
- 这种病例表明阿斯伯吉勒斯感染的非典型表现,涉及软组织.
- 组织病理学确认和分子检测对于准确的诊断至关重要.
- 在免疫受损患者的软组织质量的差异诊断中,应考虑真菌感染,包括Aspergillus.
相关概念视频
Pulmonary Tuberculosis III
1.8K
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
1.8K
Endocarditis II: Clinical Features of Infective Endocarditis
929
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
929
Fungal Phylum Microsporidia
782
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
782
Fungal Phylum Ascomycota
2.4K
Phylum Ascomycota, a major division within the subkingdom Dikarya, comprises a diverse range of fungal species, including both unicellular yeasts and filamentous molds such as Aspergillus and Penicillium. These fungi thrive in a variety of habitats, from aquatic ecosystems to terrestrial environments, playing crucial ecological and economic roles.Morphology and ReproductionThe defining characteristic of Ascomycetes, commonly referred to as sac fungi, is the ascus—a sac-like structure that...
2.4K
Atypical Pneumonia
84
Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease...
84
Asthma III: Clinical Manifestations
49
Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
49


